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my blood as data

Sometime in March I had my blood drawn at a neighbourhood GP. I had wanted to get my blood tested for years, but was unable to overcome my fear of the needle…

on coping with emotional dysregulation

I realised that I have problems regulating stress and my emotions, only sometime in the last couple of years. This reminds me of the time when I told an ex-colleague I may…

Every one of the zones

Every one of the zones, or systems, of the network—the neural, the hormonal, the gastrointestinal, and the immune—is set up to communicate with one another, via peptides and messenger-specific peptide receptors. Every second, a massive information exchange is occurring in your body. Imagine each of these messenger systems possessing a specific tone, humming a signature tune, rising and falling, waxing and waning, binding and unbinding, and if we could hear this body music with our ears, then the sum of these sounds would be the music that we call the emotions.

people who are depressed have trouble learning

It also helps explain why constantly high levels of cortisol—due to chronic stress—make it hard to learn new material, and why people who are depressed have trouble learning. It’s not just lack of motivation, it’s because the hippocampal neurons have bolstered their glutamate machinery and shut out less important stimuli. They’re obsessed with the stress.

the action of cortisol amasses a surplus fuel supply

Cortisol takes over for epinephrine and signals the liver to make more glucose available in the bloodstream, while at the same time blocking insulin receptors at nonessential tissues and organs and shutting down certain intersections so the fuel flows only to areas important to fight-or-flight. The strategy is to make the body insulin-resistant so the brain has enough glucose. Cortisol also begins restocking the shelves, so to speak, replenishing energy stores depleted by the action of epinephrine. It converts protein into glycogen and begins the process of storing fat...If this process continues unabated, as in chronic stress, the action of cortisol amasses a surplus fuel supply around the abdomen in the form of belly fat.