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the will to be truly alive

Every morning at the park I see people of all types doing their morning exercise. People exercise for different reasons. Vanity is of course a strong motivator, some people do it because…

The mind, then, is that which holds the network together

The mind, then, is that which holds the network together, often acting below our consciousness, linking and coordinating the major systems and their organs and cells in an intelligently orchestrated symphony of life. Thus, we might refer to the whole system as a psychosomatic information network, linking psyche, which comprises all that is of an ostensibly nonmaterial nature, such as mind, emotion, and soul, to soma, which is the material world of molecules, cells, and organs. Mind and body, psyche and soma.

The superior colliculus in the midbrain

The superior colliculus in the midbrain, another nodal point of neuropeptide receptors, controls the muscles that direct the eyeball, and affects which images are permitted to fall on the retina and hence to be seen.

Think of the brain as a machine

Think of the brain as a machine for not merely filtering and storing this sensory input, but for associating it with other events or stimuli occurring simultaneously at any synapse or receptor along the way—that is, learning.

Resilience is the buildup

Resilience is the buildup of these waste-disposing enzymes, neuroprotective factors, and proteins that prevent the naturally programmed death of cells. I like to think of these elements as armies that remain on duty to take on the next stress. The best way to build them up is by bringing mild stress on yourself: using the brain to learn, restricting calories, exercising, and, as Mattson and your mother would remind you, eating your vegetables.

people who are depressed have trouble learning

It also helps explain why constantly high levels of cortisol—due to chronic stress—make it hard to learn new material, and why people who are depressed have trouble learning. It’s not just lack of motivation, it’s because the hippocampal neurons have bolstered their glutamate machinery and shut out less important stimuli. They’re obsessed with the stress.